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Peptic Ulcer disease

Break in the lining of the mucosa .

 

Causes / Risk Factors

  • H. Pylori infection
  • Use of Aspirin and NSAIDS
  • Smoking
  • Gastrinoma
  • Stress
  • Type A personality
  • Excessive alcohol

Clinical features

  • Pain is typically associated with hunger , occurs at night and is often relieved by food and antacids
  • Heaburnrt
  • Chronic NSAIDS
  • Older adult patients

Tretmaent

  • Antacids
  • PPI
  • H. Pylori associated treatment

Alarm Features in patients with UGI symptoms

  • Age older than 55 years with new-onset dyspepsia
  • Family history of UGI cancer
  • GI bleeding
  • Jaundice
  • Palpable abdominal mass
  • Persistent vomiting
  • Progressive dysphagia
  • Unintended weight loss