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Inflammatory Bowel Disease

Chronic or relapsing immune activation and inflammation within the GI tracts

Types

  1. Ulcerative Colitis
  2. Crohns disease

Ulcerative Colitis

  • Disease characterized by large bowel ulceration

Clinical features

  • Abdominal pain
  • Diarrhea
  • Weight loss
  • Blood in stool
  • Urgency ( Urgent need to pass stool )

Diagnosis

  • Laboratory investigation
  • Colonoscopy
  • Fecal calprotectin

Treatment

  • Varies from colonoscopy and clinical findings
  • Treatment range from mesalamines to biologicals

Crohns disease

  • It’s a disease of small and large bowel

Clinical features

  • Pain in the umbilical region
  • Diarrhea
  • Fever
  • Abdominal lump
  • Blood in stool
  • Vomiting
  • Malabsorption
  • Weight loss

Diagnosis

  • Colonoscopy
  • CT enterography

Treatment

  • Varies from stage of disease
  • Treatment ranges from steroids, biologicals